As featured in Parade, by Laura Beck, October 2, 2026
GLP-1 medications are helping many people reach a healthier weight, but rapid weight loss can also change how the face looks. Dr. Morgana Colombo, MD, FAAD, board-certified dermatologist at Integrated Dermatology of Reston and founder of Vidaderma, was one of 10 dermatologists, cosmetic physicians, and facial plastic surgeons Parade consulted on the most common mistake people make when trying to fix "Ozempic face," and what to do instead.
What is Ozempic face?
"Ozempic face" isn't a medical diagnosis. It's a popular term for the facial changes that can come with rapid weight loss, such as flatter cheeks, hollowing, and looser skin. Dr. Colombo noted that skin quality itself takes a hit during rapid weight loss, which is why laxity needs its own attention rather than being treated as just a volume problem.
Why rushing into filler can backfire
The experts in the feature agreed that the biggest mistake is rushing into fillers too soon. Dr. Colombo explained that adding a lot of filler while you're still losing weight means:
"You are treating a moving target." Dr. Morgana Colombo, via Parade
In other words, as your weight continues to change, so does your face, and what looks right today may not look right a few months from now.
What Dr. Colombo recommends at home
Rather than trying to refill the face, the focus is on supporting the skin itself. Dr. Colombo's at-home approach includes vitamin C, peptides, and a ceramide moisturizer to keep the skin barrier steady.
For a full routine built around these changes, see Dr. Colombo's GLP-1 Skincare Guide.
In-office treatments that support the skin
Dr. Colombo's in-office options include resurfacing lasers, radiofrequency microneedling or ultrasound tightening, and biostimulatory injectables, chosen case by case.
That doesn't mean filler is off the table. Dr. Colombo was among the experts who said strategic filler has a place when there's a true structural deficit, ideally combined with treatments like lasers, biostimulators, and skin boosters.
Should Ozempic face keep you from taking a GLP-1?
No. According to Dr. Colombo, people shouldn't fear GLP-1 medications because of Ozempic face, since these changes can be managed well with an individualized plan.
A longevity approach to weight loss and skin
At Vidaderma, we believe in consistent, science-informed care over quick fixes. Explore The Skin Longevity Framework or take the skin quiz to build your routine.
Noticing more shedding too? Rapid weight loss is a common trigger. Read Dr. Colombo's guide to thinning hair in women, as featured in Who What Wear.
Frequently asked questions
Should I get filler for Ozempic face while I'm still losing weight?
Dr. Colombo cautions that adding a lot of filler mid-process means treating a moving target, since your face keeps changing as your weight does.
What skincare helps with skin changes from GLP-1 weight loss?
Dr. Colombo's at-home lineup includes vitamin C, peptides, and a ceramide moisturizer to support the skin barrier.
Can Ozempic face be treated?
Yes. Dr. Colombo says these changes can be managed well with an individualized plan, which may include lasers, radiofrequency microneedling or ultrasound tightening, biostimulatory injectables, and strategic filler when appropriate.

