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The Reverser I
Gentle Renewal Serum
- Regular price
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$140.00 - Regular price
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$140.00 - Sale price
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$140.00
A gentle retinoid acid ester HPR and niacinamide ester serum.
Suitable for all skin types except extremely sensitive skin.
Receive a $100 credit toward any non-subscription product when you sign up for a 12 month subscription. Check your email for credit code after purchase.
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Benefits
- Novel potent yet less irritating using retinoic acid combined with niacinamide
- Helps improve the appearance of fine lines, diminish pore size and uneven skin tone
- Makes skin look tighter and more lifted
FAQs & How To Use
Apply in the evening every other night, or as tolerated. For best results, alternate with a vitamin C product: use vitamin C in the morning and retinol at night, or alternate nights between vitamin C and retinol.
1. What type of retinoid is used?
The Reverser I and II use Hydroxypinacolone Retinoate (HPR), which is a more stable and tolerable retinoic-acid ester. It is comparable to prescription tretinoin, but causes less irritation, making it great for sensitive skin.
2. Who should use Reverser I vs II?
Reverser I is ideal for beginners or those with sensitive skin.
Reverser II is best for experienced retinoid users or those seeking stronger anti-aging benefits.
3. Is HPR less irritating than retinol?
Yes. Studies show HPR causes less redness and peeling than traditional retinol, while binding directly to retinoid receptors. This allows for less irritation than prescription tretinoin or other OTC retinol formulations. However, it has similar potency and efficacy to prescription tretinoin.
4. When will I see results?
Most users noticea smoother texture in 4–6 weeks of consistent use. Improvements in fine-lines typically become noticeable by 8–12 weeks.
Key Ingredients
- Hydroxypinacolone Retinoate: A vitamin A derivative that accelerates cell turnover and stimulates collagen production, reducing signs of aging, and improving skin texture.
- Niacinamide: A vitamin A derivative that accelerates cell turnover and stimulates collagen production, reducing signs of aging, and improving skin texture.
Full Ingredients
Ethyl trisiloxane, Dimethicone, Dimethicone/Vinyl dimethicone crosspolymer, Caprylic/capric triglyceride, Myristyl nicotinate, Glyceryl oleate, Hydroxypinacolone retinoate, Bisabolol, Tetrahexyldecyl ascorbate and Tocopherol
Precautions
For external use only. Avoid contact with eyes and mucosa. If contact occurs, rinse well with water. If irritation, redness, or itching occurs, discontinue use and consult physician. If pregnant or nursing, consult your physician before using this product. Keep out of reach of children.


I started using The Reverser I as part of a skincare challenge and I loved it so much I have incorporated it into my daily routine. I have very sensitive skin, so I was unable to use this daily, but I found that reducing the usage to around 2 times a week allowed me to continue using this product with ease! I've always wanted to use retinols and have been unable to due to my extreme sensitivity, but this has made it possible for even someone like me to be able to get the same benefits without worrying about brreakouts and irritation. It absorbs quickly, which I also love. My skin is brighter and I see fine lines and wrinkles gradually disappearing before my eyes! My face feels so soft and smooth, i find myself touching it sometimes in disbilief... I also love the texture of the products, you can immediately feel the quality difference is supirior to other products and the ingredient list shows how much care and thought Dr. Colombo has put into this to make it more natural and healthy compared to other beauty brands as well as making it stand out against top shelf products with its unrivaled skincare results.
I’ve been really happy with The Reverser I. It’s lightweight, absorbs quickly, and doesn’t cause the irritation I usually get from retinol.
After a few weeks, my skin looked smoother and more even, with a nice glow. Great option if you’re new to retinoids or want something effective but gentle.
🌿 Serum:
The reverser serum is a game changer. It absorbs quickly, hydrates deeply, and noticeably reduces the look of irritation and flushing. It gives my skin a healthy, even glow—something I haven’t seen in years. Added bonus, I no longer using setting spray when i apply under my makeup. .
"Very well tolerated retinoid serum that doesn’t burn on application. This is the ultimate collagen booster for perimenopause and post menopause skin."
Success Stories
AdeleThe products don't feel heavy and are really gentle. I never leave home without the Vidaderma Sunscreen.
ShameinI use Vidaderma daily and it makes my skin glow!
ChristinaThe products keep my skin very hydrated all day. I feel really confident with the results.
CourtneyVidaderma is right for me because at this point in my life I am beyond what drugstore brands can do for my skin.
What Happens Beneath the Surface Matters
Vidaderma™ medical-grade skincare is formulated with higher concentrations of active ingredients, rigorously tested for effectiveness, and developed to deliver visible results.

